Classification of mouse thymic virus as a herpesvirus.
نویسندگان
چکیده
Classical herpesvirus particles were observed by thin-section electron microscopy in thymus tissues from mice inoculated with mouse thymic virus. Intranuclear particles measured approximately 100 nm in diameter, and cytoplasmic and extracellular particles measured 135 nm in diameter. The morphology of mouse thymic virus particles together with its properties of heat and ether lability suggest that thymic virus should be classified as a member of the herpesvirus group.
منابع مشابه
Biology of mouse thymic virus, a herpesvirus of mice, and the antigenic relationship to mouse cytomegalovirus.
Mouse thymic virus (TA) is a herpesvirus which produces extensive necrosis of the thymus of newborn mice 7 to 14 days after infection. Infectious virus can be recovered from the thymus for only 10 days after infection, with highest titers occurring between days 5 and 7. In mice 5 days old or less, TA infects thymus cells and produces massive necrosis. TA also infects the salivary glands and per...
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عنوان ژورنال:
- Infection and immunity
دوره 7 2 شماره
صفحات -
تاریخ انتشار 1973